You know, I’ve been prescribing paroxetine for nearly two decades now, and I still remember the first time I saw it really work. Mrs. Kowalski, 62, came in with this crushing depression that had her convinced she was a burden to everyone. She’d tried fluoxetine, sertraline—nothing stuck. Three weeks into paroxetine 20mg, she called my office crying. Not from sadness. From relief. She said “the noise stopped.” That’s the thing about this drug—when it works, it’s almost like someone turned down the volume on the world.
