Combipres

Combipres: The Antihypertensive Combination Therapy for Resistant Hypertension - A Clinical Review So What Is Combipres, Really? Look, I’ve been in cardiology for twenty-three years now, and I’ve seen hypertension regimens come and go like fashion trends. But Combipres - that’s the fixed-dose combination of clonidine hydrochloride and chlorthalidone - has this peculiar staying power that I didn’t fully appreciate until about five years into practice. Combipres is essentially a two-drug formulation that combines a centrally acting alpha-2 agonist (clonidine 0.