Betnovate (Betamethasone Valerate): A Comprehensive Evidence-Based Review for Clinical Practice I’ve been prescribing topical corticosteroids for nearly three decades, and if I’m honest, Betnovate is one of those drugs that sits in the back pocket of every dermatologist I know. It’s not flashy, it’s not new, but when you understand its pharmacology and limitations, it’s remarkably effective. Let me walk you through what the evidence actually says, not what the marketing brochures claim.