Benzac: First-Line Topical Therapy for Acne Vulgaris – A Comprehensive Clinical Review 1. Introduction: What is Benzac? Its Role in Modern Dermatology So, you’re looking at Benzac. Let’s cut through the noise. Benzac is the brand name for a topical gel or wash containing benzoyl peroxide, typically in concentrations ranging from 2.5% to 10%. It’s been a workhorse in dermatology for decades, and honestly, it’s still one of the most cost-effective first-line agents we have for mild to moderate acne vulgaris.