Kytril (Granisetron): Antiemetic Therapy for Chemotherapy-Induced Nausea and Vomiting - Clinical Evidence and Practice Guide

Class: Antiemetic Agent, 5-HT3 Receptor Antagonist Mechanism: Selective serotonin (5-HT3) receptor blockade Route: Oral, Intravenous, Transdermal Manufacturer: Roche Laboratories (originally), now multiple generics 1. Introduction: What is Kytril? Its Role in Modern Oncology Let me be straight with you - Kytril isn’t some trendy supplement you’ll find at Whole Foods. It’s a prescription antiemetic that’s been saving patients from the misery of chemotherapy-induced nausea and vomiting (CINV) since the 1990s. I remember when we had nothing but metoclopramide and high-dose dexamethasone - patients would dread treatment days more than the disease itself.